Podwójne hamowanie mTORC1 / mTORC2 jako cel terapeutyczny

Podwójne hamowanie mTORC1 / mTORC2 jako cel terapeutyczny

Podwójne hamowanie mTORC1 / mTORC2 jako cel terapeutyczny ukierunkowany na gospodarza w patologicznie odmiennych mysich modelach gruźlicy 

Efforts to develop simpler and shorter-course therapies for tuberculosis have included a concentrate on host-directed remedy (HDT). The aim of HDT is to modulate the host response to an infection, thereby bettering immune defenses to scale back the length of antibacterial remedy and/or the quantity of lung harm.

As a mediator of innate and adaptive immune responses concerned in eliminating intracellular pathogens, autophagy is a possible goal for HDT in tuberculosis. As a result of Mycobacterium tuberculosis modulates mammalian goal of rapamycin (mTOR) signaling to impede autophagy, pharmacologic mTOR inhibition may present efficient HDT. mTOR exists inside two distinct multiprotein complexes, mTOR complex-1 (mTORC1) and mTOR complex-2 (mTORC2).

Rapamycin and its analogs solely partially inhibit mTORC1. We hypothesized that novel mTOR kinase inhibitors blocking each complexes would have expanded therapeutic potential. We in contrast the consequences of two mTOR inhibitors: rapamycin and the orally obtainable mTOR kinase area inhibitor CC214-2, which blocks each mTORC1 and mTORC2, as adjunctive therapies in opposition to murine TB, when added to the first-line routine (RHZE) or the novel bedaquiline-pretomanid-linezolid (BPaL) routine.

Neither mTOR inhibitor affected lung CFU counts after 4-Eight weeks of remedy when mixed with BPaL or RHZE. Nonetheless, addition of CC214-2 to BPaL and RHZE was related to considerably fewer relapses in C3HeB/FeJ in comparison with addition of rapamycin and, in RHZE-treated mice, resulted in fewer relapses in comparison with RHZE alone. Due to this fact, CC214-2 and associated mTOR kinase inhibitors could also be simpler candidates for HDT than rapamycin analogs and will have the potential to shorten the length of TB remedy.

 

patogeny2019
patogeny2019

Mouse antibody for M. tuberculosis ESAT6

5173 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis ESAT6 for WB, ELISA.

Recombinant M. Tuberculosis CFP10: ESAT6 Chimera protein

DAGA-193 1 mg
EUR 2042.4

Mycobacterium tuberculosis (M. tuberculosis) Antibody

abx415707-1ml 1 ml
EUR 727.2

Mycobacterium tuberculosis antibody

20-MR50 1 mg
EUR 139.2
Description: Rabbit polyclonal Mycobacterium tuberculosis antibody

Mycobacterium tuberculosis Antibody

abx022066-1mg 1 mg
EUR 1220.4

Mycobacterium tuberculosis Antibody

abx022067-1mg 1 mg
EUR 1296

Mycobacterium tuberculosis Antibody

abx022073-1mg 1 mg
EUR 1296

Mycobacterium tuberculosis Antibody

abx022087-1mg 1 mg
EUR 994.8

Mycobacterium tuberculosis Antibody

abx022088-1mg 1 mg
EUR 994.8

Mycobacterium tuberculosis Antibody

abx022089-1mg 1 mg
EUR 944.4

Mycobacterium tuberculosis Antibody

abx022090-1mg 1 mg
EUR 944.4

Mycobacterium tuberculosis Antibody

abx023092-1ml 1 ml
EUR 718.8

Mycobacterium tuberculosis RV2623 antibody

10R-M139a 1 mg
EUR 736.8
Description: Mouse monoclonal Mycobacterium tuberculosis RV2623 antibody

Mycobacterium tuberculosis CFP10 Antibody

abx022068-1mg 1 mg
EUR 1111.2

Mycobacterium tuberculosis CFP10 Antibody

abx022069-1mg 1 mg
EUR 1111.2

Mycobacterium tuberculosis CFP10 Antibody

abx022070-1mg 1 mg
EUR 1111.2

Mycobacterium tuberculosis Hsp65 Antibody

abx022091-1mg 1 mg
EUR 1296

Mycobacterium tuberculosis Antibody (FITC)

abx023089-1ml 1 ml
EUR 718.8

Mycobacterium tuberculosis Antibody (Biotin)

abx023090-1ml 1 ml
EUR 718.8

Mycobacterium tuberculosis Antibody (HRP)

abx023091-1ml 1 ml
EUR 777.6

Anti-Mycobacterium tuberculosis antibody

STJ16101444 1 mL
EUR 1005.6

CFP10-ESAT6 Protein

E5-00059 100ug
EUR 411.6

Mycobacterium tuberculosis antigen GlcB Antibody

abx140170-01mg 0.1 mg
EUR 510

Mycobacterium tuberculosis antigen Acr2 Antibody

abx140171-01mg 0.1 mg
EUR 510

Mycobacterium tuberculosis antigen Acr1 Antibody

abx140172-01mg 0.1 mg
EUR 510

Mycobacterium tuberculosis antigen Tb7.7 Antibody

abx140173-01mg 0.1 mg
EUR 510

Mycobacterium tuberculosis antigen Tb10.3 Antibody

abx140174-01mg 0.1 mg
EUR 510

CFP10 protein (Mycobacterium tuberculosis)

30R-3240 50 ug
EUR 584.4
Description: Purified recombinant CFP10 protein (Mycobacterium tuberculosis)

Aspartate transaminase Mycobacterium tuberculosis

20-abx072004
  • EUR 1095.60
  • EUR 4302.00
  • EUR 393.60
  • 190 µg
  • 1 mg
  • 40 µg

Mycobacterium Tuberculosis MoeX Protein

20-abx260302
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

Mycobacterium tuberculosis PCR kit

PCR-VH201-48D 50T
EUR 543.6

Mycobacterium tuberculosis PCR kit

PCR-VH201-96D 100T
EUR 686.4

ESAT6 protein (His tag)

80R-2222 50 ug
EUR 508.8
Description: Purified recombinant Mycobacterium tuberculosis ESAT6 Protein (His tag)

TB esat6+cfp10 antigen

DAGF-025 1mg
EUR 1263.6

Mycobacterium tuberculosis antigen CFP10 (Rv3874) Antibody

abx140047-01mg 0.1 mg
EUR 510

Mouse Anti-Mycobacterium tuberculosis Monoclonal Antibody

DMAB3972-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Mycobacterium tuberculosis Monoclonal Antibody

DMAB3972-1mg 1 mg
EUR 1762.8

Rabbit Anti-Mycobacterium tuberculosis Polyclonal Antibody

DPAB1436 1 ml
EUR 889.2

Rabbit Anti-Mycobacterium tuberculosis Polyclonal Antibody

DPAB1437 1 ml
EUR 937.2

Rabbit Anti-Mycobacterium tuberculosis Polyclonal Antibody

DPAB1439 1 ml
EUR 937.2

Rabbit Anti Mycobacterium Tuberculosis Polyclonal Antibody

DPBT-66904RM 1 ml
EUR 1033.2

Goat Mycobacterium Tuberculosis Antibody ELISA kit

E06M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Mycobacterium Tuberculosis Antibody ELISA kit

E06M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Mycobacterium Tuberculosis Antibody ELISA kit

E06M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Mycobacterium Tuberculosis Antibody ELISA kit

E04M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Mycobacterium Tuberculosis Antibody ELISA kit

E04M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Mycobacterium Tuberculosis Antibody ELISA kit

E04M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Mycobacterium Tuberculosis Antibody ELISA kit

E01M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Mycobacterium Tuberculosis Antibody ELISA kit

E01M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Mycobacterium Tuberculosis Antibody ELISA kit

E01M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mycobacterium Tuberculosis Antibody ELISA kit

E03M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mycobacterium Tuberculosis Antibody ELISA kit

E03M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mycobacterium Tuberculosis Antibody ELISA kit

E03M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mycobacterium Tuberculosis Antibody ELISA kit

E09M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mycobacterium Tuberculosis Antibody ELISA kit

E09M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mycobacterium Tuberculosis Antibody ELISA kit

E09M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mycobacterium Tuberculosis Antibody ELISA kit

E02M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mycobacterium Tuberculosis Antibody ELISA kit

E02M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mycobacterium Tuberculosis Antibody ELISA kit

E02M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mycobacterium Tuberculosis Antibody ELISA kit

E08M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mycobacterium Tuberculosis Antibody ELISA kit

E08M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mycobacterium Tuberculosis Antibody ELISA kit

E08M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Mycobacterium Tuberculosis Antibody ELISA kit

E07M0338-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Mycobacterium Tuberculosis Antibody ELISA kit

E07M0338-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Mycobacterium Tuberculosis Antibody ELISA kit

E07M0338-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Mycobacterium Tuberculosis Antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mycobacterium tuberculosis 16 kDa Antigen (M. tuberculosis 16 kDa) Antibody

abx415759-01mg 0.1 mg
EUR 760.8

Mycobacterium tuberculosis 38 kDa Antigen (M. tuberculosis 38 kDa) Antibody

abx411025-02mg 0.2 mg
EUR 678

Imidazoleglycerol-phosphate dehydratase Mycobacterium tuberculosis

20-abx072006
  • EUR 3232.80
  • EUR 1095.60
  • EUR 393.60
  • 1 mg
  • 260 µg
  • 50 ug

Mycobacterium tuberculosis Thymidylate kinase (tmk)

1-CSB-EP007226MVZ
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mycobacterium tuberculosis Thymidylate kinase(tmk) expressed in E.coli

Mycobacterium tuberculosis IgG ELISA Kit

DEIA381 96T
EUR 674.4
Description: The Mycobacterium tuberculosis IgG antibody ELISA kit has been designed for the detection andthe quantitative determination of specific IgG antibodies against Mycobacterium tuberculosis in serum and plasma.

Mycobacterium tuberculosis IgA ELISA Kit

DEIA382 96T
EUR 696
Description: The Mycobacterium tuberculosis IgA antibody ELISA kit has been designed for the detection andthe quantitative determination of specific IgA antibodies against Mycobacterium tuberculosis in serum and plasma.

Mycobacterium tuberculosis IgM ELISA Kit

DEIA383 96T
EUR 696
Description: The Mycobacterium tuberculosis IgM antibody ELISA kit has been designed for the detection andthe quantitative determination of specific IgM antibodies against Mycobacterium tuberculosis in serum and plasma.

Mycobacterium tuberculosis Adenylate kinase (adk)

1-CSB-EP404243MON
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mycobacterium tuberculosis Adenylate kinase(adk) expressed in E.coli

Mycobacterium tuberculosis Mycothione reductase (mtr)

1-CSB-EP517031MVZ
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mycobacterium tuberculosis Mycothione reductase(mtr) expressed in E.coli

Mycobacterium tuberculosis Toxin RelG (relG)

1-CSB-EP521896MVZ
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mycobacterium tuberculosis Toxin RelG(relG) expressed in E.coli

Mycobacterium tuberculosis Antitoxin MT2731 (MT2731)

1-CSB-YP300323MVZ
  • EUR 814.80
  • EUR 402.00
  • EUR 2606.40
  • EUR 1261.20
  • EUR 1730.40
  • EUR 522.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mycobacterium tuberculosis Antitoxin MT2731(MT2731) expressed in Yeast

Mycobacterium tuberculosis RT PCR kit

RTq-VH201-100D 100T
EUR 860.4

Mycobacterium tuberculosis RT PCR kit

RTq-VH201-150D 150T
EUR 969.6

Mycobacterium tuberculosis RT PCR kit

RTq-VH201-50D 50T
EUR 717.6

Inactivated Mycobacterium Tuberculosis Chimeric Antigen

VAng-Yyj0001-1mg 1 mg
EUR 2053.2
Description: Mycobacterium Tuberculosis Chimeric Antigen, native protein.

Recombinant Mycobacterium Tuberculosis CFP10 Protein

VAng-Yyj0026-100g 100 µg
EUR 1309.2
Description: Mycobacterium Tuberculosis CFP10, recombinant protein.

Recombinant Mycobacterium Tuberculosis CFP10 Protein

VAng-Yyj0026-1mg 1 mg
EUR 3092.4
Description: Mycobacterium Tuberculosis CFP10, recombinant protein.

Recombinant Mycobacterium Tuberculosis CFP10 Protein

VAng-Yyj0026-500g 500 µg
EUR 2200.8
Description: Mycobacterium Tuberculosis CFP10, recombinant protein.

Recombinant Mycobacterium Tuberculosis clpB Protein

VAng-Yyj0029-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Chaperone protein ClpB (clpB), recombinant protein.

Recombinant Mycobacterium Tuberculosis dnaG Protein

VAng-Yyj0038-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis DNA primase (dnaG), recombinant protein.

Recombinant Mycobacterium Tuberculosis dnaK Protein

VAng-Yyj0039-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Chaperone protein DnaK (dnaK), recombinant protein.

Recombinant Mycobacterium Tuberculosis fbiC Protein

VAng-Yyj0045-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis FO synthase (fbiC), recombinant protein.

Recombinant Mycobacterium Tuberculosis HSP Protein

VAng-Yyj0063-10g 10 µg
EUR 2250
Description: Mycobacterium Tuberculosis, HSP, recombinant protein.

Recombinant Mycobacterium Tuberculosis htpG Protein

VAng-Yyj0064-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Chaperone protein htpG (htpG), recombinant protein.

Recombinant Mycobacterium Tuberculosis malQ Protein

VAng-Yyj0086-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis 4-alpha-glucanotransferase (malQ), recombinant protein.

Recombinant Mycobacterium Tuberculosis MbtB Protein

VAng-Yyj0092-1mgEcoli 1 mg (E. coli)
EUR 4924.8
Description: Mycobacterium Tuberculosis Phenyloxazoline synthase MbtB (mbtB), recombinant protein.

Recombinant Mycobacterium Tuberculosis MbtB Protein

VAng-Yyj0092-500gEcoli 500 µg (E. coli)
EUR 3303.6
Description: Mycobacterium Tuberculosis Phenyloxazoline synthase MbtB (mbtB), recombinant protein.

Recombinant Mycobacterium Tuberculosis mmpL10 Protein

VAng-Yyj0097-1mgEcoli 1 mg (E. coli)
EUR 4594.8
Description: Mycobacterium Tuberculosis Putative membrane protein mmpL10 (mmpL10), recombinant protein.

Recombinant Mycobacterium Tuberculosis MoeX Protein

VAng-Yyj0100-100g 100 µg
EUR 804
Description: Mycobacterium Tuberculosis MoeX, recombinant protein.

Recombinant Mycobacterium Tuberculosis MoeX Protein

VAng-Yyj0100-1mg 1 mg
EUR 3781.2
Description: Mycobacterium Tuberculosis MoeX, recombinant protein.

Recombinant Mycobacterium Tuberculosis MoeX Protein

VAng-Yyj0100-500g 500 µg
EUR 2187.6
Description: Mycobacterium Tuberculosis MoeX, recombinant protein.

Recombinant Mycobacterium Tuberculosis mpa Protein

VAng-Yyj0101-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Proteasome-associated ATPase (mpa), recombinant protein.

Recombinant Mycobacterium Tuberculosis plsB1 Protein

VAng-Yyj0125-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Putative acyltransferase plsB1 (plsB1), recombinant protein.

Recombinant Mycobacterium Tuberculosis ppe11 Protein

VAng-Yyj0128-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Uncharacterized PPE family protein PPE11 (ppe11), recombinant protein.

Recombinant Mycobacterium Tuberculosis ppe12 Protein

VAng-Yyj0129-inquire inquire Ask for price
Description: Mycobacterium Tuberculosis Uncharacterized PPE family protein PPE12 (ppe12), recombinant protein.

Reprezentowanie przenoszenia gruźlicy ze złożonym zakażeniem: podejście do modelowania symulacyjnego opartego na agentach

Goal: A latest research reported a tuberculosis (TB) outbreak through which, amongst newly contaminated people, publicity to extra energetic infections was related to a better likelihood of creating energetic illness. Known as complicated contagion, a number of reexposures to TB inside a brief interval after preliminary an infection is hypothesized to confer a better chance of creating energetic an infection in 1 y. The aim of this text is to develop and validate an agent-based simulation mannequin (ABM) to review the impact of complicated contagion on population-level TB transmission dynamics.

Strategies: We constructed an ABM of a TB epidemic utilizing knowledge from a sequence of outbreaks recorded within the 20th century in Saskatchewan, Canada. We match three dynamical schemes: base, with no complicated contagion; additive, through which every reexposure confers an unbiased threat of activated an infection; and threshold, through which a small variety of reexposures confers a low threat and a excessive variety of reexposures confers a excessive threat of activation.

Outcomes: We discover that the bottom mannequin suits the mortality and incidence output targets greatest, adopted by the edge after which the additive fashions. The edge mannequin suits the incidence higher than the bottom mannequin does however overestimates mortality. All three fashions produce qualitatively lifelike epidemic curves.

Conclusion: We discover that complicated contagion qualitatively modifications the trajectory of a TB epidemic, though knowledge from a high-incidence setting are reproduced higher with the bottom mannequin. Outcomes from this mannequin show the feasibility of utilizing ABM to seize nuances in TB transmission.

Opis przypadku gruźlicy w palcu 

Tuberculosis is a persistent, infectious illness that predominantly impacts the respiratory system. Of the least frequent extrapulmonary types of the illness is cutaneous tuberculosis. We current an uncommon case, which is of cutaneous tuberculosis within the finger, manifesting as an ulcerating, erythematous lesion. This had later unfold to the adjoining tender tissue and bones, inflicting osteomyelitis of the phalanges. It will be significant that physicians keep a excessive index of suspicion when confronted with atypical pores and skin lesions to keep away from the sequelae of the native and disseminated unfold of a tuberculosis an infection.

Gruźlica pozapłucna udająca złośliwość ściany klatki piersiowej: po prostu nigdy nie przestaje zaskakiwać! 

With the emergence of the acquired immunodeficiency syndrome, we witnessed a better incidence of disseminated and extrapulmonary tuberculosis. The an infection websites generally embody lymph nodes, pleura, and osteoarticular areas, though any organ will be concerned. Given the atypical presentation of the extrapulmonary illness, it poses a big diagnostic problem for the physicians; due to this fact, a excessive index of suspicion needs to be maintained, significantly the place tuberculosis is endemic. Right here we current a case of remoted chest wall tuberculosis in an immunocompetent affected person.

Weryfikacja modelu choroby opartego na czynnikach ludzkiego zakażenia Mycobacterium tuberculosis

phenomena in many various utility areas. Nonetheless, one of the crucial points, poorly investigated within the literature, regards an vital step of the mannequin credibility evaluation: resolution verification. This research overcomes this limitation by proposing a common verification framework for Agent-Primarily based Fashions that goals at evaluating the numerical errors related with the mannequin.

A step-by-step process, which consists of two essential verification research (deterministic and stochastic mannequin verification), is described intimately and utilized to a selected mission crucial situation: the quantification of the numerical approximation error for UISS-TB, an ABM of the human immune system developed to foretell the development of pulmonary tuberculosis.

Outcomes present indications on the risk to use the proposed mannequin verification workflow to systematically determine and quantify numerical approximation errors related to UISS-TB and, usually, with some other ABMs. This text is protected by copyright. All rights reserved.

Podtytuł immunologiczny w gruźlicy utajonej 

  • Latent tuberculosis an infection (LTBI) poses a serious roadblock within the international effort to eradicate tuberculosis (TB). A deep understanding of the host responses concerned in institution and upkeep of TB latency is required to propel the event of delicate strategies to detect and deal with LTBI. Provided that LTBI people are usually asymptomatic, it’s difficult to distinguish latently contaminated from uninfected people.
  • A significant contributor to this downside is that no clear sample of host response is linked with LTBI, as molecular correlates of latent an infection have been arduous to determine. On this research, we now have analyzed the worldwide perturbations in host response in LTBI people as in comparison with uninfected people and significantly the heterogeneity in such response, throughout LTBI cohorts.
  • For this, we constructed individualized genome-wide host response networks knowledgeable by blood transcriptomes for 136 LTBI circumstances and have used a delicate community mining algorithm to determine top-ranked host response subnetworks in every case.
  • Our evaluation signifies that regardless of the excessive heterogeneity within the gene expression profiles amongst LTBI samples, clear patterns of perturbation are present in the immune response pathways, resulting in grouping LTBI samples into Four totally different immune-subtypes. Our outcomes recommend that totally different subnetworks of molecular perturbations are related to latent tuberculosis.

Macaca mulatta Gonadotropin-releasing hormone II receptor (GNRHR2)

1-CSB-CF856800MOW(M)
  • EUR 1596.00
  • EUR 724.80
  • EUR 1032.00
  • 1MG
  • 200ug
  • 500ug
Description: Recombinant Macaca mulatta Gonadotropin-releasing hormone II receptor(GNRHR2) expressed in in vitro E.coli expression system

Crassostrea gigas A-kinase anchor protein 7 isoform X2

1-CSB-EP2586DXQ(M)e1
  • EUR 872.40
  • EUR 510.00
  • EUR 2331.60
  • EUR 1266.00
  • EUR 1602.00
  • EUR 615.60
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Crassostrea gigas A-kinase anchor protein 7 isoform X2 expressed in E.coli

Crassostrea gigas A-kinase anchor protein 7 isoform X2

1-CSB-EP2586DXQ(M)f1
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Crassostrea gigas A-kinase anchor protein 7 isoform X2 expressed in E.coli

Monoclonal Anti-M. tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2) IgG

HSP651-M 100 ul
EUR 578.4

Mycobacterium tuberculosis (M. tuberculosis) Antibody

abx415707-1ml 1 ml
EUR 727.2

Human Heat Shock Protein 65(HSP-65)ELISA Kit

YLA0243HU-48T 48T
EUR 435

Human Heat Shock Protein 65(HSP-65)ELISA Kit

YLA0243HU-96T 96T
EUR 562.5

M. Tuberculosis LAM

DAGA-168 1 mg
EUR 1434

M. Tuberculosis MPT53

DAGA-171 100 µg
EUR 868.8

Recombinant Mycobacterium Tuberculosis HSP Protein

VAng-Yyj0063-10g 10 µg
EUR 2250
Description: Mycobacterium Tuberculosis, HSP, recombinant protein.

Monoclonal Anti-M. tuberculosis 10 Kda cultural filtrate protein (CFP10) IgG

CFP101-M 100 ul
EUR 578.4

Monoclonal Anti-M. tuberculosis Rv1734 dormant protein from H37Rv strain IgG

RV17341-M 100 ul
EUR 578.4

Monoclonal Anti-M. tuberculosis Rv2031 dormant protein from H37Rv strain IgG

RV20311-M 100 ul
EUR 578.4

Monoclonal Anti-M. tuberculosis Rv2623 dormant protein from H37Rv strain IgG

RV26231-M 100 ul
EUR 578.4

Mycobacterium tuberculosis HSP 70 Recombinant Protein

53-349 0.01 mg
EUR 789.9
Description: Mycobacterium tuberculosis HSP 70 Recombinant Protein

M. Tuberculosis 15.3 kDa

DAGA-169 1 mg
EUR 1170

M. Tuberculosis Rv0192A Antigen

DAGA-173 100 µg
EUR 868.8

M. Tuberculosis Rv2672 Antigen

DAGA-174 100 µg
EUR 868.8

M. Tuberculosis Rv0398c Antigen

DAGA-176 100 µg
EUR 868.8

M. Tuberculosis Rv2253 Antigen

DAGA-177 100 µg
EUR 868.8

M. Tuberculosis MT3413 Antigen

DAGA-178 100 µg
EUR 868.8

M. Tuberculosis Rv0477 Antigen

DAGA-179 100 µg
EUR 868.8

M. Tuberculosis Mpt70 Antigen

DAGA-182 100 µg
EUR 868.8

M. Tuberculosis MPT83 Antigen

DAGA-183 100 µg
EUR 868.8

M. Tuberculosis Mpt64 Antigen

DAGA-184 100 µg
EUR 868.8

M. Tuberculosis TB22.2 Antigen

DAGA-186 100 µg
EUR 868.8

Recombinant M. Tuberculosis HSP65

DAGA-194 0.1 mg Ask for price

M. Tuberculosis 38 kDa

DAG-T2447 1 mg Ask for price

M. Tuberculosis 16 kDa

DAG-T2449 1 mg Ask for price

M. Tuberculosis HSP70 Protein

abx060544-100ug 100 ug
EUR 1378.8

M. tuberculosis CFP10, Protein

abx061400-100ug 100 ug
EUR 961.2

M. tuberculosis ESAT6, Protein

abx061402-100ug 100 ug
EUR 910.8

Monoclonal Anti-M. tuberculosis 10 Kda cultural filtrate protein (CFP10) IgG #2

CFP102-M 100 ul
EUR 578.4

Monoclonal Anti-M. tuberculosis Heat Shock Protein 70 (hsp70/Dnak/ML2496) IgG

HSP701-M 100 ul
EUR 578.4

Recombinant Myobacterium Tuberculosis Heat Shock Protein 65

7-07048 2µg Ask for price

Recombinant Myobacterium Tuberculosis Heat Shock Protein 65

7-07049 10µg Ask for price

Recombinant Myobacterium Tuberculosis Heat Shock Protein 65

7-07050 100µg Ask for price

Myobacterium Tuberculosis Heat Shock Protein 65 Protein

20-abx263477
  • EUR 2047.20
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Recombinant M. Tuberculosis CFP-10

DAGA-170 1 mg
EUR 790.8

M. Tuberculosis 85-C Antigen

DAGA-175 100 µg
EUR 868.8

M. Tuberculosis Mpt63/MPB63 Antigen

DAGA-180 100 µg
EUR 868.8

M. Tuberculosis 85-A Antigen

DAGA-181 100 µg
EUR 868.8

M. Tuberculosis 85-B Antigen

DAGA-185 100 µg
EUR 868.8

M. Tuberculosis ESAT-6 Antigen

DAGA-187 100 µg
EUR 868.8

M. Tuberculosis 85A Antigen[his]

DAGA-189 10 µg
EUR 812.4

M. Tuberculosis 48 kDa protein

DAGA-191 1 mg Ask for price

M. Tuberculosis 85A Antigen [His]

DAGA-192 50 µg
EUR 1228.8

Recombinant M. Tuberculosis Moex antigen

DAGA-213 1 mg Ask for price

Anti-Acr1 (M. tuberculosis) Purified

11-185-C100 0.1 mg
EUR 244.8

Anti-Tb10.4 (M. tuberculosis) Purified

11-186-C100 0.1 mg
EUR 244.8

Anti-Tb10.3 (M. tuberculosis) Purified

11-187-C100 0.1 mg
EUR 244.8

Anti-Acr2 (M. tuberculosis) Purified

11-188-C100 0.1 mg
EUR 244.8

Anti-Ag85b (M. tuberculosis) Purified

11-189-C100 0.1 mg
EUR 244.8

Anti-Tb7.7 (M. tuberculosis) Purified

11-190-C100 0.1 mg
EUR 244.8

Anti-GlcB (M. tuberculosis) Purified

11-192-C100 0.1 mg
EUR 244.8

M. Tuberculosis 38 kDa Protein

abx060636-100ug 100 ug
EUR 978

Zmp1 M. tuberculosis Recombinant Protein

90-361 50 ug
EUR 752.1
Description: M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and peptides and are involved in many important processes such as blood pressure regulation (Neprilysin or NEP1), cardiovascular development (Endothelin Converting Enzyme-1 or ECE-12), prevention of haemolytic reaction (KELL) and phosphate homeostasis (PHEX). Zmp1 is a soluble enzyme member of the M13 endopeptidases family that plays a key role in Mycobacterium tuberculosis pathogenicity with a still unknown mechanism. Recently, it was shown to suppress inflammasome activation by inhibiting caspase-1 activation, thus preventing processing of pro-IL-1beta into IL-1beta and the consequent phagosome maturation.

Ubiquitin 2 (Ub2, 65-76) peptide with anti-M. tuberculosis activity (STLHLVLRLRGG, MW:1321.6)

UBQ151-P 1 mg
EUR 182.4

Recombinant Mycobacterium Tuberculosis rpmD Protein (aa 1-65)

VAng-Yyj0608-50gEcoli 50 µg (E. coli)
EUR 1562.4
Description: Mycobacterium Tuberculosis 50S ribosomal protein L30 (rpmD), recombinant protein.

M. Tuberculosis p60-Related Protein Rv0024

DAGA-172 100 µg
EUR 868.8

M. Tuberculosis EsxB (LHP) (CFP10) Antigen

DAGA-188 100 µg
EUR 868.8

M. Tuberculosis 63 kDa protein [His]

DAGA-190 1 mg Ask for price

Rabbit polyclonal antibody for M. tuberculosis

4603 1 ml
EUR 360.16
Description: This is FITC conjugated rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

Rabbit polyclonal antibody for M. tuberculosis

4607 1 ml
EUR 360.16
Description: This is Biotin conjugated rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

Mouse antibody for M. tuberculosis CFP10

5172 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis CFP10 for WB, ELISA.

Mouse antibody for M. tuberculosis ESAT6

5173 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis ESAT6 for WB, ELISA.

Mouse antibody for M. tuberculosis 38kDa

5174 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis 38kDa for WB, ELISA.

Mouse antibody for M. tuberculosis Hsp65

5177 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis Hsp65 for WB, ELISA.

Mouse antibody for M. tuberculosis Hsp65

5178 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis Hsp65 for WB, ELISA.

Anti-CFP-10 (M. tuberculosis) Purified

11-490-C025 0.025 mg
EUR 146.4

Anti-CFP-10 (M. tuberculosis) Purified

11-490-C100 0.1 mg
EUR 244.8

Anti-ESAT-6 (M. tuberculosis) Purified

11-491-C025 0.025 mg
EUR 146.4

Anti-ESAT-6 (M. tuberculosis) Purified

11-491-C100 0.1 mg
EUR 244.8

Rabbit polyclonal antibody for M. tuberculosis

304 1 ml
EUR 386.26
Description: This is HRP conjugated rabbit polyclonal antibody against M tuberculosis all antigens for WB, ELISA.

M. tuberculosis 38 kDa recombinant antigen

8811 100 ug
EUR 477.6
Description: This is M. tuberculosis 38 kDa recombinant antigen for ELISA,WB.

NAD Kinase M. tuberculosis Recombinant Protein

90-365 50 ug
EUR 651.3
Description: NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+

NAD Synthetase M. tuberculosis Recombinant Protein

90-366 50 ug
EUR 752.1
Description: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate

M. Tuberculosis ClpP Protease Assay Kit

TBP100K 100 assays
EUR 278.4
Description: This product includes 3100 ul of Assay Buffer and 310 ul of 10 x Substrate and 3500 ul of Stop solution. It is for 100 assays in 384-well plate format

Mycobacterium tuberculosis 16 kDa Antigen (M. tuberculosis 16 kDa) Antibody

abx415759-01mg 0.1 mg
EUR 760.8

Mycobacterium tuberculosis 38 kDa Antigen (M. tuberculosis 38 kDa) Antibody

abx411025-02mg 0.2 mg
EUR 678

Recombinant purified M. tuberculosis Heat Shock Protein 65 (hsp65/groEL-2/Cpn60-2) control for Western

HSP651-C 100 ul
EUR 343.2

Recombinant M. Tuberculosis CFP10: ESAT6 Chimera protein

DAGA-193 1 mg
EUR 2042.4

Recombinant M. Tuberculosis EspC/Rv3615c(H37Rv) [His]

DAGA-3055 100ug
EUR 764.4

Mouse antibody for M. tuberculosis 16 kDa

5175 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis 16 kDa for WB, ELISA.

Mouse antibody for M. tuberculosis 16 kDa

5176 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against M tuberculosis 16 kDa for WB, ELISA.

Pyrroline-5-caroxylate reductase, M. tuberculosis Recombinant

P1456-10 each
EUR 314.4

Pyrroline-5-caroxylate reductase, M. tuberculosis Recombinant

P1456-50 each
EUR 1083.6

M. Tuberculosis ClpP Protease Assay Kit Plus

TBP100KE 100 assays
EUR 467.15
Description: This product includes 3000 ul of Assay Buffer, 310 ul of 10 x Substrate, 3500 ul of Stop solution and 31 ul of 100 x Mtb ClpP1P2 protease. It is for 100 assays in 384-well plate format

Mouse Anti-Mycobacterium tuberculosis Heat Shock Protein 65 Monoclonal Antibody

DMAB3971-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Mycobacterium tuberculosis Heat Shock Protein 65 Monoclonal Antibody

DMAB3971-1mg 1 mg
EUR 1762.8

Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase [NADH] (M. tuberculosis inhA) Antibody

20-abx109426
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

HSP

EF006920 96 Tests
EUR 826.8

Monoclonal Anti-Mycobacterium tuberculosis antigen (16kDa/Hspx) IgG

MTB161-M 100 ul
EUR 578.4

Monoclonal Anti-Mycobacterium tuberculosis antigen 38kDa/Ag85B IgG

MTB381-M 100 ul
EUR 578.4

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-100ug

QP7004-ye-100ug 100ug
EUR 945.6

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-10ug

QP7004-ye-10ug 10ug
EUR 434.4

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-1mg

QP7004-ye-1mg 1mg
EUR 3296.4

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-200ug

QP7004-ye-200ug 200ug
EUR 1512

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-500ug

QP7004-ye-500ug 500ug
EUR 2164.8

Recombinant M. tuberculosis Ag85B Protein, His, Yeast-50ug

QP7004-ye-50ug 50ug
EUR 576

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-100ug

QP7382-ec-100ug 100ug
EUR 848.4

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-10ug

QP7382-ec-10ug 10ug
EUR 391.2

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-1mg

QP7382-ec-1mg 1mg
EUR 2763.6

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-200ug

QP7382-ec-200ug 200ug
EUR 1338

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-500ug

QP7382-ec-500ug 500ug
EUR 1816.8

Recombinant M. tuberculosis Ag85C Protein, His, E.coli-50ug

QP7382-ec-50ug 50ug
EUR 522

Recombinant M. tuberculosis INHA Protein, His, Yeast-100ug

QP7385-ye-100ug 100ug
EUR 945.6

Recombinant M. tuberculosis INHA Protein, His, Yeast-10ug

QP7385-ye-10ug 10ug
EUR 434.4

Recombinant M. tuberculosis INHA Protein, His, Yeast-1mg

QP7385-ye-1mg 1mg
EUR 3296.4

Recombinant M. tuberculosis INHA Protein, His, Yeast-200ug

QP7385-ye-200ug 200ug
EUR 1512

Recombinant M. tuberculosis INHA Protein, His, Yeast-500ug

QP7385-ye-500ug 500ug
EUR 2164.8

Recombinant M. tuberculosis INHA Protein, His, Yeast-50ug

QP7385-ye-50ug 50ug
EUR 576

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-100ug

QP8929-ec-100ug 100ug
EUR 848.4

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-10ug

QP8929-ec-10ug 10ug
EUR 391.2

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-1mg

QP8929-ec-1mg 1mg
EUR 2763.6

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-200ug

QP8929-ec-200ug 200ug
EUR 1338

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-500ug

QP8929-ec-500ug 500ug
EUR 1816.8

Recombinant M. tuberculosis Ag85A Protein, His, E.coli-50ug

QP8929-ec-50ug 50ug
EUR 522

HCG?Anti-Human Chorionic Gonadotrophin Antibody IgG) ELISA test

65 96T/Box Ask for price
Description: ELISA based test for quantitative detection of HCG?Anti-Human Chorionic Gonadotrophin Antibody IgG)

Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase [NADH] (M. tuberculosis inhA) Antibody (HRP)

20-abx109170
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase [NADH] (M. tuberculosis inhA) Antibody (Biotin)

20-abx106339
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Mycobacterium tuberculosis Enoyl-[acyl-carrier-protein] reductase [NADH] (M. tuberculosis inhA) Antibody (FITC)

20-abx107752
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Monoclonal Anti-Mycobacterium tuberculosis antigen (6kDa/ESAT-6) IgG

MTB061-M 100 ul
EUR 578.4

B7-H4 CHO Cell Line-78586-M

78586-M 2 vials
EUR 7150
Description: B7-H4 CHO Cell line is a recombinant clonal stable CHO-K1 cell line constitutively expressing full length human B7-H4 protein, also known as V-set domain-containing T-cell activation inhibitor 1 (VTCN1); (NM_024626.4). Surface expression of B7-H4 was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of B7-H4 expression (Medium and High), to mimic different B7-H4 expression levels in various cancer types.

Mouse Monoclonal Anti-Zaire Ebola virus (killed) IgG (mixture of EVZ12-M and EVZ13-M), aff pure

EVZ14-M 100 ul
EUR 578.4

Ammonium Bromide - 3 M (100ml)

M-CSS-423 1 Unit
EUR 85
Description: Ammonium Bromide - 3 M (100ml)

Imidazole, 1 M (100 ml)

M-CSS-512 4 x 25 ml
EUR 79
Description: Imidazole, 1 M (100 ml)

IgG Antibody to M. Tuberculosis, TB-IgG ELISA Kit

DEIA083 96T
EUR 676.8
Description: This kit is anenzyme-linked immunosorbent assay for qualitative detection of IgG antibodies to Mycobacterium tuberculosis in human serum or plasma. It is intended for diagnosing and monitoring of patients related to infection by M. tuberculosis and other Mycobacteria.

Recombinant M. tuberculosis Ag85B Protein, His-SUMO, E.coli-100ug

QP7004-ec-100ug 100ug
EUR 848.4

Recombinant M. tuberculosis Ag85B Protein, His-SUMO, E.coli-1mg

QP7004-ec-1mg 1mg
EUR 2763.6

Recombinant M. tuberculosis Ag85B Protein, His-SUMO, E.coli-200ug

QP7004-ec-200ug 200ug
EUR 1338

Recombinant M. tuberculosis Ag85B Protein, His-SUMO, E.coli-500ug

QP7004-ec-500ug 500ug
EUR 1816.8

Recombinant M. tuberculosis Ag85B Protein, His-SUMO, E.coli-50ug

QP7004-ec-50ug 50ug
EUR 522

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-100ug

QP7385-ec-100ug 100ug
EUR 848.4

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-10ug

QP7385-ec-10ug 10ug
EUR 391.2

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-1mg

QP7385-ec-1mg 1mg
EUR 2763.6

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-200ug

QP7385-ec-200ug 200ug
EUR 1338

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-500ug

QP7385-ec-500ug 500ug
EUR 1816.8

Recombinant M. tuberculosis INHA Protein, His-SUMO, E.coli-50ug

QP7385-ec-50ug 50ug
EUR 522

Recombinant M. tuberculosis Antitoxin MT2731 Protein, His, Yeast-10ug

QP9476-ye-10ug 10ug
EUR 434.4

Recombinant M. tuberculosis Antitoxin MT2731 Protein, His, Yeast-1mg

QP9476-ye-1mg 1mg
EUR 3296.4

Recombinant M. tuberculosis Antitoxin MT2731 Protein, His, Yeast-200ug

QP9476-ye-200ug 200ug
EUR 1512

Recombinant M. tuberculosis Antitoxin MT2731 Protein, His, Yeast-500ug

QP9476-ye-500ug 500ug
EUR 2164.8

Recombinant M. tuberculosis Antitoxin MT2731 Protein, His, Yeast-50ug

QP9476-ye-50ug 50ug
EUR 576

HSP antibody

10R-10337 100 ug
EUR 522
Description: Mouse monoclonal HSP antibody

HSP Antibody

abx018126-100ug 100 ug
EUR 526.8

AM4-65

70039 1MG
EUR 360
Description: Minimum order quantity: 1 unit of 1MG

Claudin-18 Isoform 2 CHO Cell Line-78533-M

78533-M 2 vials
EUR 7150
Description: Recombinant clonal CHO cell line stably expressing full length human claudin 18.2 (claudin 18 isoform 2, CLDN 18.2, gene accession number NM_001002026.3). The stable clonal cell line was selected for different levels of Claudin 18.2 expression (High, Medium, and Low) compared to the parental CHO-K1 cell line.

1,6-Hexanediol, 5 M, 100 ML

M-CSS-109 100 ml
EUR 70
Description: 1,6-Hexanediol, 5 M, 100 ML

Ammonium Acetate, 5 M, 100 ML

M-CSS-129 100 ml
EUR 70
Description: Ammonium Acetate, 5 M, 100 ML

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